Global Innovation Systems (GIS) is a subject that studies and introduces the combination of creativity and innovation in global business. The course helps managers to develop a cross-border innovation system, combining innovation within enterprises and national-regional and global innovation systems. Therefore, the subject develops skills in nurturing a culture of innovation in competitive change, technology in building and integrating global innovation achievement, risk management and operations management. multinational innovation. In addition, the course provides skills to set up GIS, change people skills to integrate new technology and wide applicability in GIS. The course is divided into 3 parts; the first part discusses the principles of GIS governance, the second highlights the role GIS plays in global businesses, and the last part introduces GIS integrated solutions in national-regional-global innovation.